iPSC and Regenerative Medicine

We generate personalised patient derived induced pluripotent stem cells (iPSCs) from somatic cells such as blood and skin cells. Towards our goal, we develop and apply novel differentiation protocols to direct differentiation of the iPSCs, with an emphasis on ocular cells such as the corneal and retinal cell phenotypes, organoids along with derivation of skeletal muscle cells to address yet untreatable diseases such as Duchenne Muscular dystrophy (DMD).

We use the iPSC derived cells towards our approach of relevant disease modelling of ocular, skeletal and metabolic diseases to dissect the disease mechanisms in order to identify novel drug targets and deliver possible curative cell transplants. Focusing on iPSC biology we explore, innovate and develop culture mediums to maximize the pluripotency of iPSCs and optimize their differentiation potentials to diverse cellular phenotypes.